Stopping immune suppression after stem cell transplant
Treatments studied
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests whether it's safe to stop one type of anti-rejection medication (tacrolimus) earlier than usual after a stem cell transplant from a matched donor. If you qualify, you may be able to reduce your long-term medication burden.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 80 years old.
- You must have one of these blood cancers: AML, MDS, myelofibrosis, CML, or CMML.
- You must be scheduled for your first stem cell transplant using a specific conditioning regimen.
- You must have a fully matched (8/8) related or unrelated donor.
- Your kidney, heart, lung, and liver function must be within certain limits.
- You must not have had a previous stem cell transplant or certain active infections or cancers.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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