Minocycline after successful stroke clot removal in the back brain
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This study tests whether an antibiotic called minocycline can reduce brain damage after doctors successfully remove a blood clot from the back of the brain (posterior circulation stroke) using a catheter procedure. The drug may help protect brain tissue and improve recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- 18 years or older
- Stroke symptoms started within the last 24 hours (or upon waking up)
- Moderate to severe stroke symptoms (NIHSS score of 6 or higher)
- Brain imaging shows good tissue remaining in the back of the brain (ASPECTS score of 6 or higher)
- Blood clot successfully removed from the vertebral or basilar artery in the back of the brain
- Able to give written consent or have a legal representative do so
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests whether an antibiotic called minocycline, given alongside standard stroke treatment (clot-busting medication), can help reduce brain damage and improve recovery. You would receive minocycline around the time of your clot-busting treatment.
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