Study of brain activity during nerve stimulation for depression
Part of Mental health clinical trials.
This study looks at how vagus nerve stimulation (VNS) affects brain activity, using EEG and MRI, in people already implanted with a VNS device for depression. Participation may help researchers understand how this treatment works and improve future care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 18 years old.
- You are already enrolled in the REVEAL study and have a VNS implant for depression.
- You have had chronic depression (2+ years) or at least 4 depressive episodes, confirmed by a psychiatrist.
- You can read and speak English well enough to complete questionnaires and follow instructions.
- You are not pregnant and agree to use effective birth control if you could become pregnant.
- You have no metal in your body that would make an MRI unsafe, and you are otherwise in good health.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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