Ultrasound-guided esmolol for septic shock
Treatments studied
Part of Infections clinical trials.
This study tests whether a medicine called esmolol, which slows the heart rate, can help people with septic shock (a severe infection that causes very low blood pressure) when their heart is beating too fast. Doctors will use ultrasound to make sure it's safe before giving the medicine.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You were diagnosed with septic shock within the last 24 hours
- You are in the intensive care unit (ICU) within the last 72 hours
- Your heart rate is 100 beats per minute or higher (from a normal rhythm or an irregular rhythm like atrial fibrillation)
- You are not already taking a beta-blocker or calcium channel blocker medicine
- You are not pregnant, and you do not have a known allergy to beta-blockers, certain heart rhythm problems, or active asthma
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a medication called esmolol (a short-acting beta-blocker) to see if it can improve blood flow in tiny blood vessels (microcirculation) and help stabilize blood pressure in people with septic shock who have a fast heart rate. The goal is to see if slowing the heart rate can improve organ function and recovery.
This study tests whether using ultrasound (heart imaging and blood-vessel scanning) helps doctors treat septic shock—a life-threatening blood infection—more effectively. The trial measures whether these imaging tools help guide fluid and medication decisions during resuscitation.
This trial tests whether a heart-rate–controlling medication can better manage a new fast heart rhythm that happens during sepsis shock. It may help reduce heart strain and improve safety compared with standard care.
This trial compares the use of a simple ultrasound test of the lungs and heart to help doctors decide how much fluid to give adults with septic shock. The goal is to find the most accurate way to guide treatment, which could lead to better recovery.
This trial looks at how well the heart and blood vessels are working in people with septic shock. It helps doctors decide the best way to reduce blood pressure medication safely.
This trial tests whether landiolol (a short-acting heart-rate–lowering medicine) can reduce deaths compared with standard care in people in septic shock who have a fast heart rate and strong heart pumping. It is meant for a very specific type of critically ill patient while they are on a breathing machine.
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