CAR-T cell therapy for autoimmune diseases
Part of Brain & nervous system, Cancer, Immune system & allergy clinical trials.
This trial tests a new kind of cell therapy (UCAR-T) that targets CD19 and BCMA proteins on immune cells. It is for people with certain neurological autoimmune diseases like multiple sclerosis, myasthenia gravis, chronic inflammatory demyelinating polyneuropathy, or autoimmune encephalitis who have not responded well to standard treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18 to 70 years old
- Diagnosed with one of these conditions: multiple sclerosis, myasthenia gravis, chronic inflammatory demyelinating polyneuropathy, or autoimmune encephalitis
- Have tried at least one standard treatment that did not work well enough or caused side effects
- Have adequate organ function (liver, kidneys, blood counts, heart and lungs)
- Not pregnant or breastfeeding, and willing to use effective birth control during and for a year after treatment
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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