Comparing two medicines for antipsychotic-related weight gain
Treatments studied
Part of Mental health clinical trials.
This study compares two medications, dapagliflozin and metformin, to help reduce weight gain caused by antipsychotic drugs. If you've gained weight since starting an antipsychotic, this trial may offer a way to manage that side effect.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be at least 16 years old.
- You must have a mental health condition (like schizophrenia, bipolar, or depression) for which you're taking antipsychotic medicine.
- You must have been on the same antipsychotic for at least 3 months.
- You must have gained significant weight since starting the antipsychotic, either at least 7% of your starting weight or a BMI over 25.
- You cannot have diabetes, PCOS, serious kidney or liver problems, or be pregnant or breastfeeding.
- You cannot be taking certain other medications that cause weight gain or have used weight-loss programs recently.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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