Mouthpiece for better sleep in healthy adults
Part of Brain & nervous system, Mental health clinical trials.
This study tests a custom mouthpiece (like a dental retainer) to see if it can improve your sleep quality and heart health during sleep. If you are a healthy adult aged 40–65 with a normal to slightly high weight and a desk job, you may be able to join.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 40 and 65 years old.
- You are generally healthy and do not have a diagnosed sleep disorder (like sleep apnea).
- Your BMI is between 25 and 35.
- You have a full set of natural teeth up to your back molars and are not wearing braces or dentures.
- You do not smoke, vape, or use tobacco products.
- You work in a desk job or professional role (not manual labor).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two common treatments for moderate sleep apnea: a custom mouthpiece that gently advances your jaw, and a CPAP machine that blows air to keep your airway open. The goal is to see which treatment works better for improving sleep and daytime symptoms.
This trial tests whether a special mouthguard (called a mandibular advancement device) can help with both sleep apnea and nighttime heartburn. If you have mild or moderate sleep apnea and reflux, this device might improve your symptoms without needing a CPAP machine.
This study tests whether using an anti-snoring mouth guard (a mandibular advancement appliance) can help keep your airway open during sleep if you have obstructive sleep apnea. If you’re referred for this kind of mouth guard, the trial will see if using it more regularly or in a specific way improves symptoms or breathing during sleep.
This study looks at a new way to use digital dental scans to fit a mouthpiece that treats obstructive sleep apnea. If you use this mouthpiece, the study may help make fitting more comfortable and accurate.
This study looks at people with sleep apnea who are using a special mouthpiece (mandibular advancement device). It aims to find out which factors predict changes in how your teeth fit together after using the device.
This study tests whether specific mouth and throat exercises can help people with sleep apnea who already use a mandibular advancement device (a type of mouthguard). The goal is to see if adding exercises improves sleep and breathing.
Hear when a new Sleep trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.