Hibernation-like therapy for acute ischemic stroke
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether giving a combination of two medicines (chlorpromazine and promethazine) to put the body into a 'hibernation-like' state can help people having a severe stroke. You will also receive standard clot-removal treatment, and the study hopes to see if this approach improves recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 80 years old.
- You had a stroke within the last 24 hours and are eligible for a procedure to remove the clot (endovascular therapy).
- You had a brain scan confirming a blockage in a main artery, with no bleeding, and some salvageable brain tissue.
- You were able to manage your daily activities before this stroke (no significant disability).
- You do not have severe bleeding, infections, heart disease, or certain other conditions that could make the study unsafe.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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