Adding lumateperone for depression after early-life trauma
Treatments studied
Part of Mental health clinical trials.
This trial tests whether adding a medication called lumateperone to your current antidepressant helps depression in people who experienced early-life trauma. It also uses brain scans to understand how the treatment works.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 21 and 70 years old.
- You must have a diagnosis of major depression (without psychosis).
- You must have experienced physical or sexual assault before age 16.
- You must have been on a stable antidepressant for at least 6 weeks without enough improvement.
- You must be willing to have brain MRI scans.
- You must not be at high risk for suicide or have certain medical conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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