Deep brain stimulation for tough-to-treat depression
Treatments studied
Part of Mental health clinical trials.
This early trial tests a personalized deep brain stimulation (DBS) approach for people with major depression that hasn't improved with at least two different antidepressants. DBS uses small electrodes placed in the brain to adjust mood-related circuits.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have major depression (diagnosed by a psychiatrist using DSM-5 criteria).
- You've had depression for at least 12 months and tried two or more antidepressants that didn't work.
- Your depression is severe (score of 20 or higher on a standard depression questionnaire).
- You don't have other serious medical conditions, epilepsy, or a recent history of suicide attempts.
- You are not pregnant, breastfeeding, or planning pregnancy during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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