Continuing cetuximab after first treatment stops working for metastatic colorectal cancer
Treatments studied
Part of Cancer, Digestive system clinical trials.
This trial tests if continuing the targeted therapy cetuximab after initial treatment stops working can help people with advanced colorectal cancer. Participants have a specific gene profile (RAS and BRAF normal) and their cancer responds well at first.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have metastatic colorectal cancer (cancer that has spread).
- Your first treatment included cetuximab or a similar drug, and it worked well for at least 6 months or shrunk tumors significantly.
- That treatment has now stopped working (cancer has progressed).
- You have a specific genetic type: RAS and BRAF genes are normal (wild-type).
- You are healthy enough for daily activities (ECOG score 0 or 1).
- You are 18 years or older.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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