Study of SHR-1918 for high cholesterol not controlled by statins and PCSK9 inhibitors
Treatments studied
Part of Hormones & metabolism clinical trials.
This trial tests a new medicine, SHR-1918, for people whose bad cholesterol (LDL-C) stays high even when they take statins and another type of cholesterol-lowering drug called a PCSK9 inhibitor. It aims to see if this additional treatment can lower their cholesterol more effectively.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 85 years old.
- Your triglycerides (blood fats) are below a certain level.
- Your bad cholesterol is at a certain level depending on your heart disease risk.
- You are taking statins and a PCSK9 inhibitor but still have high cholesterol.
- You have no severe allergies to similar drugs, recent heart problems, or uncontrolled diabetes.
- You agree to avoid pregnancy or sperm donation and use birth control during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new injectable medication called HST101 for lowering cholesterol in people who are already taking cholesterol pills but still have high levels. It may help if you have heart disease or are at high risk.
This trial tests an investigational medicine (SHR-1918) added to your current statin therapy to see if it helps lower your LDL ('bad') cholesterol and triglycerides more than a placebo. It may be an option if you're on a statin but still have high cholesterol.
This trial tests an investigational injection called SYH2070 to lower cholesterol and triglycerides in people who are already on a stable statin therapy. It may be a new option for those with mixed hyperlipidemia who need additional lipid control.
This trial tests a new medication, SHR-1918, to lower high triglyceride levels. It may be an option for people with moderately elevated triglycerides and controlled cholesterol.
This trial continues to test a drug called SHR-1918, which may help lower very high cholesterol in people with a genetic condition called homozygous familial hypercholesterolemia. It looks at whether the drug remains effective and safe over a longer period of time.
This study tests an experimental drug called HRS-1301 to see if it safely lowers LDL ("bad") cholesterol in people with high cholesterol. It is for adults who either already have artery disease or are at higher risk for it.
Hear when a new Hypercholesterolemia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.