Testing a new drug for sepsis-related lung injury
Part of Infections, Lungs & breathing clinical trials.
This trial tests a new medicine called YD0743 for people who have both sepsis (a serious infection) and ARDS (a severe lung injury from the infection). The goal is to see if the medicine helps improve breathing and survival.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have sepsis and a lung condition called ARDS that is likely caused by the sepsis.
- Your ARDS diagnosis was made within the last 48 hours.
- You are not on a life-support machine called ECMO for your lungs.
- You do not have a known bleeding disorder, low platelet count, or active bleeding.
- You are not pregnant or breastfeeding, and do not plan to become pregnant in the next 6 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at the air sacs (alveoli) in your lungs to understand how they are affected by sepsis and a related condition called ARDS. By sampling the fluid in your lungs through a bronchoscopy, researchers hope to find new ways to treat and prevent lung damage.
This study is testing a new tool to predict how well people with pneumonia or sepsis will recover. If you have either infection and are 18 or older, you may be able to join.
This trial tests if a new drug, AZD4144, can help people with sepsis-related acute kidney injury in the ICU. It aims to see if the drug can improve kidney recovery and reduce complications.
This study tests an experimental drug (STSA-1002) for people with severe breathing problems caused by a viral infection. It aims to see if the drug can help improve oxygen levels and reduce the need for a breathing machine.
This trial tests a combination of two medicines (Sivelestat Sodium and Dexamethasone) to see if they can help people with severe lung injury (ARDS) who need a breathing machine. It is for patients whose condition has just worsened and who are on a ventilator early in their illness.
This trial tests whether the steroid dexamethasone can help people with sepsis who develop acute respiratory distress syndrome (ARDS), a severe lung injury. If you have an infection and need breathing support, this study may help find a better treatment.
Hear when a new Sepsis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.