MitraClip procedure for atrial functional mitral regurgitation
Part of Heart & circulation clinical trials.
This trial tests a minimally invasive procedure to repair a leaky mitral valve in people with a specific type of heart failure. The goal is to see if the procedure, called transcatheter edge-to-edge repair (TEER), is safe and effective in reducing symptoms and improving heart function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have severe mitral regurgitation (a leaky mitral valve) caused by atrial fibrillation or heart failure with preserved ejection fraction (HFpEF).
- Your heart's pumping function (ejection fraction) must be at least 40%.
- Your left atrium (the upper heart chamber) must be enlarged, and your left ventricle (main pumping chamber) must not be severely enlarged.
- You must have symptoms like shortness of breath or fatigue despite being on recommended heart medications for at least 2 months.
- Your blood pressure and heart rate must be within certain limits, and you must be able to take blood thinners as needed.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a minimally invasive procedure (transcatheter edge-to-edge repair) to fix a leaky mitral valve caused by an enlarged atrium, not by heart muscle damage. It might be an option if your mitral regurgitation is related to atrial issues and your heart's pumping strength is normal.
This study tests a procedure that combines two treatments: fixing a leaky heart valve (mitral regurgitation) and treating an irregular heartbeat (atrial fibrillation) at the same time. It aims to improve symptoms and heart function in people with both conditions.
This study tests a minimally invasive procedure (edge-to-edge repair) for people whose mitral valve leaks because of an enlarged upper heart chamber (atrial functional mitral regurgitation). The goal is to see if this clip repair improves symptoms and outcomes compared with standard medical therapy alone.
This trial tests a new device that is placed using a thin tube through a vein in the leg to repair a leaky mitral valve in people with heart failure. The goal is to see if it can reduce symptoms and improve quality of life beyond what usual medications can do.
This trial tests a new catheter-based device to fix a leaky mitral valve without open-heart surgery. It is for people whose severe mitral regurgitation puts them at high risk for traditional surgery.
This trial tests a minimally invasive procedure to fix a leaky mitral valve in people with ATTR-CM. The procedure, called edge-to-edge repair, uses a catheter to clip the valve, which may improve symptoms and quality of life.
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