Personalized immune cell therapy for melanoma in the brain lining
Part of Brain & nervous system, Cancer, Immune system & allergy clinical trials.
This trial tests a new kind of therapy where your own immune cells (called T cells) are taken, specially trained to attack your melanoma, and then given back into the fluid around your brain and spinal cord. The goal is to see if this can help treat melanoma that has spread to that area.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have melanoma that has spread to the lining around the brain or spinal cord (confirmed by imaging or spinal fluid test).
- You need to be 18 or older and have a certain blood type marker called HLA-A2 or HLA-A24.
- You should be in good general condition (able to do most daily activities, with some effort if needed).
- You can remain on certain other treatments like targeted therapy or some immunotherapies, but must have stopped other treatments for a few days to weeks first.
- If you could become pregnant, you must agree to use effective birth control during the study and for a few months after.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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