Trial of a pig liver device for advanced liver failure
Part of Brain & nervous system, Digestive system, Hormones & metabolism clinical trials.
This trial tests a device that uses a specially pig liver to help people with severe, sudden liver failure who cannot get a transplant. It aims to support the liver until it recovers or a transplant becomes possible.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old.
- You have severe liver failure (Grade 2-3 ACLF) and a high organ failure score.
- You are not eligible for a liver transplant right now.
- You have some confusion or drowsiness due to your liver (hepatic encephalopathy).
- You or a loved one can give permission for the study.
- You have not had an organ transplant before.
- You do not have an active infection, HIV, or untreated hepatitis.
- You do not have advanced heart or lung disease or active bleeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new liver dialysis device called DIALIVE 2.0 for people with acute-on-chronic liver failure (a sudden, severe worsening of chronic liver disease). If you qualify, the device will help filter your blood, similar to kidney dialysis, to support your liver while it tries to recover.
This trial tests a procedure that filters harmful substances from your blood using a special machine. It is for people with severe liver failure (acute-on-chronic) who have signs of inflammation throughout the body.
This trial is testing new scoring systems to better predict how patients with acute-on-chronic liver failure will do. It may help doctors make more informed treatment decisions for people with this serious liver condition.
This trial tests two different blood-filtering treatments for people with severe liver failure who are waiting for or unable to receive a liver transplant. It aims to see how these treatments affect blood clotting, inflammation, and organ function.
This trial tests whether a treatment called therapeutic plasma exchange (a process that filters your blood) can help improve the function of other organs in people with severe liver failure. It aims to see if this treatment leads to better outcomes and to find markers that predict who will benefit.
This trial tests a device called CytoSorb that filters the blood to reduce inflammation in patients with sudden worsening of chronic liver disease. It may help support organ function and recovery.
Hear when a new Acute on Chronic Liver Failure (ACLF) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.