Pig liver support for acute-on-chronic liver failure
Part of Brain & nervous system, Digestive system, Hormones & metabolism clinical trials.
This study tests an investigational liver support device that uses a pig liver to help filter your blood when your liver is failing. It is for people with acute-on-chronic liver failure who are not eligible for a transplant, and it aims to give your liver time to recover or bridge you to a future transplant.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 70 years old.
- You must have acute-on-chronic liver failure (a sudden worsening of long-term liver disease) with confusion or other brain symptoms.
- You cannot be eligible for a liver transplant at the time of joining.
- You cannot have had a prior organ transplant.
- You cannot have HIV, active hepatitis B or C, active infections, or cancer requiring ongoing treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new liver dialysis device called DIALIVE 2.0 for people with acute-on-chronic liver failure (a sudden, severe worsening of chronic liver disease). If you qualify, the device will help filter your blood, similar to kidney dialysis, to support your liver while it tries to recover.
This trial tests whether giving a smaller amount of a blood-cleaning treatment (plasma exchange) can help people with sudden liver failure on top of long-term liver disease. It aims to improve liver function and overall outcomes.
This trial tests a procedure that cleans your blood (called plasma exchange) given at half the usual dose, along with other detox methods, to help people with sudden liver failure. It aims to help your liver recover or support you while you wait for a transplant.
This study tests a blood-filtering system called CytoSorb in people with severe liver failure that also affects other organs. It aims to see if removing toxins from the blood can help reduce damage and improve recovery.
This study tests a treatment that cleans your blood to help your liver recover if you have sudden liver failure. It may improve your chances of getting better.
This trial tests two different blood-filtering treatments for people with severe liver failure who are waiting for or unable to receive a liver transplant. It aims to see how these treatments affect blood clotting, inflammation, and organ function.
Hear when a new Acute on Chronic Liver Failure (ACLF) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.