Ultrasound-guided clot-busting for moderate-risk pulmonary embolism
Part of Heart & circulation, Lungs & breathing clinical trials.
This trial tests a procedure that uses ultrasound to guide a catheter that delivers clot-dissolving medicine directly to a blood clot in the lungs. It is for people who have a pulmonary embolism that causes some heart strain but who are not in shock.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have a confirmed blood clot in a lung artery seen on a CT scan
- Your blood pressure is stable (not in shock)
- Your heart shows signs of strain from the clot, like an enlarged right ventricle
- Your blood has elevated troponin (a heart muscle protein) levels
- You have at least one sign of higher risk, such as fast heartbeat, low oxygen level, or slightly low blood pressure
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new catheter-based device that delivers clot-dissolving medicine directly to the blood clot in the lungs for people with a moderate-risk pulmonary embolism. The goal is to improve blood flow to the lungs and relieve symptoms with a lower dose of medication than standard care.
This trial tests a treatment that uses ultrasound to guide a thin tube (catheter) to deliver clot-busting medicine directly into the blood clot in your lung. It may be an option for people whose clot is serious but not yet causing shock, and who have symptoms that started within the last two weeks.
This trial tests whether a standard procedure using a catheter to deliver clot-dissolving medicine directly into the lung artery works well for people with a serious but not immediately life-threatening blood clot in the lungs (pulmonary embolism). It aims to improve heart function and reduce long-term complications.
This trial compares three treatments for an intermediate-high risk pulmonary embolism: a minimally invasive clot removal procedure (embolectomy), a low-dose clot-dissolving medication, or standard blood thinning (heparin). The goal is to see which approach works best to prevent worsening while reducing bleeding risks.
This trial tests three ways of using a catheter (a thin tube) to remove or break up blood clots in the lungs for people with a serious but stable type of pulmonary embolism. The goal is to find the best approach to improve recovery and reduce complications.
This study compares different real-world treatments for a serious but stable type of blood clot in the lungs (called intermediate-high risk pulmonary embolism). It aims to see which treatments work best in everyday patients, including those with other health conditions.
Hear when a new Pulmonary Embolism (PE) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.