Clin2
NCT07433283Possibly a fitRecruiting

Iron nanoparticle injection for advanced solid tumors

Tumor, SolidLung CancerPancreas CancerThyroid CancerColorectal CancerCervical CancerVulva Cancer

Part of Cancer, Digestive system, Hormones & metabolism, Lungs & breathing, Women’s health & pregnancy clinical trials.

This trial tests a new treatment for advanced solid tumors that uses tiny iron particles guided by carbon nanoparticles, injected directly into the tumor. It may be an option if standard treatments have stopped working or aren't available, and you have a tumor that can be safely injected.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
54 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • You have an advanced solid tumor (like lung, breast, colon, or pancreatic cancer) that hasn't responded to standard treatments or for which no standard treatment exists.
  • You have at least one tumor that can be safely injected with the study drug, and it's measurable on imaging scans.
  • You are between 18 and 80 years old, and your overall health is good enough to be up and about (ECOG score 0-1).
  • Your blood counts, kidney and liver function are within acceptable limits, and your heart function is normal (LVEF ≥ 50%).
  • You are not pregnant, and you agree to use effective contraception during and for 6 months after treatment.
  • You do not have conditions that affect iron metabolism (like thalassemia or G6PD deficiency), active brain metastases, or uncontrolled infections.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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