Akkermansia and Berberine for night shift workers' insulin sensitivity
Part of Brain & nervous system, Hormones & metabolism clinical trials.
This trial tests whether taking a probiotic called Akkermansia muciniphila and a natural plant compound called berberine can improve how your body uses insulin. If you work night shifts regularly, this study may help you find a way to support your metabolic health.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must work in healthcare or industry, at least 24 hours per week.
- You must currently work night shifts (at least 3 hours between midnight and 5 a.m.) with at least 2 consecutive nights per month.
- You must have been working night shifts for more than 3 years.
- You must have 4 or more night shifts each month.
- You cannot have diabetes (type 1 or type 2), severe obesity (BMI 40 or above), or certain chronic health conditions.
- You cannot be pregnant, planning pregnancy, or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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