Catheter treatment for moderate-risk blood clots in the lungs
Part of Heart & circulation, Lungs & breathing clinical trials.
This study tests a new catheter-based device that delivers clot-dissolving medicine directly to the blood clot in the lungs for people with a moderate-risk pulmonary embolism. The goal is to improve blood flow to the lungs and relieve symptoms with a lower dose of medication than standard care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 18 and 75 years old.
- Have a diagnosis of pulmonary embolism (blood clot in the lung) within the last 14 days.
- The blood clot must be in a main lung artery as seen on a CT scan.
- Be stable enough to receive blood thinners and the study device.
- Not be pregnant, not currently receiving chemotherapy for cancer, and have no recent major bleeding or surgery.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a procedure that uses ultrasound to guide a catheter that delivers clot-dissolving medicine directly to a blood clot in the lungs. It is for people who have a pulmonary embolism that causes some heart strain but who are not in shock.
This trial tests whether a standard procedure using a catheter to deliver clot-dissolving medicine directly into the lung artery works well for people with a serious but not immediately life-threatening blood clot in the lungs (pulmonary embolism). It aims to improve heart function and reduce long-term complications.
This Phase 3 trial tests a catheter-based procedure to remove a lung blood clot (pulmonary embolism) and reduce strain on the heart. It may help people who have specific CT scan signs of right-heart strain.
This study looks at how well a catheter (a thin tube) works to treat a serious type of blood clot in the lungs. It is for people who have a large clot that is causing problems like fast heart rate or low blood pressure.
This trial tests two ways to treat a serious blood clot in the lungs: removing the clot with a small tube (catheter) alone, or combining that with a low dose of clot-dissolving medicine. The goal is to find a safer and effective treatment for people who can't have standard clot-busting treatment.
This trial tests a treatment that uses ultrasound to guide a thin tube (catheter) to deliver clot-busting medicine directly into the blood clot in your lung. It may be an option for people whose clot is serious but not yet causing shock, and who have symptoms that started within the last two weeks.
Hear when a new Pulmonary Embolism (PE) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.