Clinical trials
Aphasia clinical trials
Below are recruiting aphasia clinical trials, each written for real people, not researchers. We’re tracking 95 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07219680Recruiting
Communication quality of life in primary progressive aphasia
This trial tests a therapy to improve communication for people with primary progressive aphasia (PPA), a condition that slowly affects language. You and a care partner will attend video sessions to work on communication goals together.
Austin, TexasAges 40 years+ - NCT07036406RecruitingPhase 2
Comparing two aphasia speech therapies
This study compares two types of speech therapy for people with aphasia: one uses word-finding practice alone, and the other adds training on self-awareness and repair strategies. It aims to find which approach works better for improving communication.
New York, New YorkAges 18–89 - NCT07281313Recruiting
Exercise for aphasia after stroke
This trial tests whether a regular exercise program can help people with aphasia (trouble speaking or understanding language) after a stroke. It focuses on safety and improving language and physical health.
Berkeley, CaliforniaAges 18–80 - NCT06649084Enrolling by invitation
Language treatment study for primary progressive aphasia
This study tests a multi-component language treatment for people with primary progressive aphasia (a type of dementia that first affects language). It aims to help improve communication skills with support from a study partner.
Austin, TexasAges Any age - NCT07260253Recruiting
Remote brain stimulation for language in primary progressive aphasia
This study tests if a non-invasive brain stimulation technique called tDCS, done at home with remote supervision, can help improve language skills in people with the logopenic variant of primary progressive aphasia (PPA).
San Francisco, CaliforniaAges 40 years+ - NCT05741853Recruiting
Speech therapy study for bilingual people with primary progressive aphasia
This study looks at how well speech-language therapy works in bilingual people with primary progressive aphasia, a condition that gradually affects language. It also tests whether different language skills (Spanish/Catalan or Spanish/English) affect response to treatment.
Austin, TexasAges 40 years+ - NCT06511752RecruitingEarly Phase 1
Support group for Spanish/English speakers with progressive aphasia
This trial tests a support group program for people with progressive aphasia (a language disorder that gets worse over time) and their caregivers. The groups meet online to share experiences and learn together.
Austin, TexasAges 18 years+ - NCT06990997Recruiting
Do aphasia ID cards help service workers understand?
This study tests if identification cards that explain aphasia help service workers better understand people with aphasia. Service workers will listen to or read messages and answer questions.
Springfield, MassachusettsAges 18–59 - NCT05386394RecruitingPhase 2
Brain stimulation to help primary progressive aphasia speech
This trial tests a non-painful brain stimulation method to improve language and speech problems caused by primary progressive aphasia. It may help some people communicate more clearly by targeting specific brain regions.
Baltimore, MarylandAges 50–90 - NCT06842745RecruitingPhase 2
Brain stimulation plus language therapy for mild aphasia
This study tests whether combining brain stimulation (TMS) with language therapy can help people with mild aphasia after a stroke. It aims to improve speaking and understanding.
Philadelphia, PennsylvaniaAges 40–85 - NCT07688551RecruitingPhase 2/Phase 3
Speech therapy with brain stimulation for aphasia after stroke
This trial tests if adding a gentle brain stimulation (tDCS) to speech therapy helps people with aphasia (trouble speaking) after a stroke. If you had a stroke more than 6 months ago and have trouble naming objects, this study may be a good fit.
Charleston, South CarolinaAges 25–80 - NCT03313011Recruiting
Study brain patterns in progressive apraxia of speech
This study looks at brain changes in two types of progressive apraxia of speech, a condition that slowly worsens speech clarity. It may help researchers better understand the brain basis of your speech symptoms and how these types differ.
Rochester, MinnesotaAges 18 years+ - NCT04604444Recruiting
Rehab program to improve speech brain plasticity after stroke
This study looks at how intensive therapy can change the brain’s ability to relearn speech after a stroke that caused language or speech planning problems. You may be a good candidate if your stroke-related aphasia or apraxia was diagnosed by a speech specialist about 7 months ago.
UppsalaAges 18–75 - NCT05443633Recruiting
Brain and speech training for people with aphasia
This study looks at ways to improve language (speaking and understanding) for people with aphasia caused by stroke or dementia, using MRI to study brain function. It may help by testing language-focused approaches and how brain activity changes during treatment.
Tucson, ArizonaAges 21–80 - NCT06829420Recruiting
Mirroring speech to help people with aphasia talk better
This study tests a new way to help people who have trouble speaking after a stroke by having them mirror and follow along with recorded phrases. It is for adults who had a stroke on the left side of their brain and now have nonfluent aphasia (trouble getting words out).
Tampa, FloridaAges 18–70 - NCT06968663RecruitingPhase 2
Brain stimulation with speech therapy for recent stroke aphasia
This study tests if adding a non-invasive brain stimulation technique (transcranial magnetic stimulation) to language therapy can improve speech recovery in people who had a stroke 2 to 6 weeks ago and now have aphasia (trouble speaking or understanding language).
Philadelphia, PennsylvaniaAges 18–85 - NCT01818661RecruitingPhase 4
Imaging study for progressive apraxia of speech
This trial uses repeated brain scans to study how progressive apraxia of speech changes over time. It may help doctors better understand the condition and improve future tracking and care.
Rochester, MinnesotaAges 18 years+ - NCT06678854Enrolling by invitation
Communication Training for Madison Police Officers
This study tests a training program designed to help first responders and law enforcement officers communicate better with people who have aphasia (a language disorder affecting speaking and understanding). If you work for the Madison Police Department, you may be able to join.
Madison, WisconsinAges 18 years+ - NCT05901233Enrolling by invitation
Remote brain stimulation and speech therapy for primary progressive aphasia
This study tests whether combining speech-language treatment with remotely supervised brain stimulation (a mild current to the scalp) can improve communication in people with primary progressive aphasia. You and a study partner would also join online training and regular video check-ins.
San Francisco, CaliforniaAges Any age - NCT04957537Recruiting
Speech and meaning therapy for primary progressive semantic aphasia
This study tests a “semantic rehabilitation” program—therapy focused on improving word meaning and understanding—for people with primary progressive semantic aphasia. If you qualify, it may help slow or improve language difficulties and daily communication.
ToulouseAges 18–100 - NCT07700537Recruiting
Brain stimulation for speech recovery after recent stroke
This study tests a gentle brain stimulation treatment called tDCS to help people recover speech after a recent stroke. If you had a first-time stroke on the left side of your brain within the past 3 months and now have trouble speaking (aphasia), this treatment may help your brain relearn language.
Hefei, AnhuiAges 18–80 - NCT07346378Recruiting
Brain stimulation for post-stroke aphasia
This study tests a new type of brain stimulation called temporal interference stimulation to see if it can safely help people recover language abilities after a stroke. It aims to improve communication for people with post-stroke aphasia.
Hefei, AnhuiAges 18–80 - NCT04363684Recruiting
Study of frontotemporal dementia and related syndromes over time
This study follows people with frontotemporal dementia (FTLD) and related conditions, and collects health and (for some people) body fluid information, to understand how these illnesses change over time. It may help researchers track disease signs and find better ways to measure progression.
Birmingham, AlabamaAges 18 years+ - NCT03843463RecruitingPhase 2
Escitalopram plus language therapy after left stroke
This trial tests whether the antidepressant medicine escitalopram, along with language therapy, can improve language skills after a recent stroke that affected the left side of the brain. It may help some people with stroke-related aphasia (language difficulty) regain words and communication.
Baltimore, MarylandAges 18–99
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Aphasia trials by city
Studies with a site in or near these metro areas.
Aphasia trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for aphasia?
- Yes. Clin2 currently lists 95 recruiting aphasia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a aphasia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a aphasia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.