Botulinum toxin vs. surgery for certain types of crossed eyes
Treatments studied
Part of Brain & nervous system, Eyes & vision clinical trials.
This trial compares a toxin injection (Botulinum Toxin A) to traditional eye muscle surgery for children with certain types of esotropia (crossed eyes). It aims to see which treatment works better for angles between 10 and 30 prism diopters.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a type of crossed eye (esotropia) that started before 6 months of age (infantile) or after 6 months (acquired non-accommodative or partially accommodative), with an eye turn between 10 and 30 prism diopters.
- You are between 4 months and 17 years old for infantile esotropia, or between 6 months and 17 years for the acquired types.
- You have not had botulinum toxin injections or eye muscle surgery before for crossed eyes.
- You have no significant health problems affecting the brain or eyes, such as cerebral palsy, hydrocephalus, or optic nerve issues.
- You are not severely nearsighted (myopia less than 6.00 diopters) and can wear glasses if needed for at least 2 weeks before joining.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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