Botulinum toxin injection vs eye muscle surgery for inward turning eyes
Treatments studied
Part of Brain & nervous system, Eyes & vision clinical trials.
This study compares two treatments for esotropia (inward turning of the eyes) in children and teens. One treatment is an injection of botulinum toxin (Botox) into the eye muscle, and the other is traditional eye muscle surgery. The goal is to see which treatment works better for improving eye alignment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child must be between 4 months and 17 years old.
- Your child must have a constant or intermittent inward turning of the eye (esotropia) that is between 10 and 30 prism diopters (a measure of eye misalignment).
- The inward turning must be either infantile (started before 6 months of age), acquired non-accommodative (started after 6 months and not fully corrected by glasses), or acquired partially accommodative (partially corrected by glasses but still has residual turning).
- If your child has significant farsightedness, they must wear glasses for at least 2 weeks before joining.
- Your child must not have had prior eye muscle surgery, Botox injections for strabismus, or certain eye or brain conditions.
- Your child must have been born after 34 weeks of pregnancy and weighed more than 1500 grams (about 3.3 pounds) at birth.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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