Memantine and raloxifene for brain protection during radiation
Treatments studied
Part of Brain & nervous system, Cancer clinical trials.
This trial tests whether two medications, memantine and raloxifene, can help protect memory and thinking abilities during radiation therapy for brain tumors. It is for people who are about to start or have started radiation therapy for a solid tumor in the brain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are currently having radiation therapy for a solid tumor in your brain, either IMRT or whole brain radiation.
- You have not had radiation to the brain before.
- You are not allergic to memantine or raloxifene.
- Your kidney function is good (creatinine clearance of 50 mL/min or more).
- Your memory and thinking are reasonably intact (score of 17 or higher on a standard test).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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