Medications to protect memory during brain radiation
Treatments studied
Part of Genetic & congenital, Injuries & trauma, Mental health clinical trials.
This study tests whether two medications, memantine and pioglitazone, can help protect your memory and thinking skills during and after radiation therapy for brain tumors. It may help you keep your mental sharpness while treating the cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed cancer that has spread to the brain (usually from another part of the body).
- You have not had radiation therapy to the brain before.
- Your brain tumors are not located near the memory center (hippocampus) and have not spread to the lining of the brain.
- You are relatively active and can care for yourself (Karnofsky score of 70 or higher).
- Your blood counts, liver function, and kidney function are within acceptable ranges for the study.
- You have not had surgery to drain fluid from the brain (shunt), and you are not pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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