Heart cell injection during bypass surgery for advanced heart failure
Part of Heart & circulation clinical trials.
This study tests whether injecting special heart cells (called HiCM-188) into the heart during bypass surgery can help improve heart function in people with advanced heart failure. The goal is to see if the cells can strengthen the heart muscle and help you feel better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have been diagnosed with advanced heart failure (NYHA class III to IV), meaning you feel short of breath or tired even with light activity or at rest.
- You are already scheduled to have heart bypass surgery (also called CABG).
- Your heart's pumping ability (ejection fraction) is between 20% and 45%.
- The wall of your heart is thick enough (at least 8 mm) in the areas where the cells would be injected.
- You do not have other serious heart conditions like viral myocarditis (heart muscle inflammation), amyloidosis (abnormal protein buildup), or certain valve or rhythm problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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