Clin2
NCT07480928Possibly a fitRecruiting

CAR-NK cell therapy for advanced pancreatic cancer

Pancreatic Ductal Adenocarcinoma (PDAC)Unresectable Locally Advanced or Metastatic Disease

Treatments studied

Part of Cancer, Digestive system, Hormones & metabolism clinical trials.

This trial tests a new type of immune cell therapy called CAR-NK cells that target two proteins (MSLN and MUC1) often found on pancreatic cancer cells. It is for people whose cancer has spread or cannot be removed, and who have already tried at least one standard treatment.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
42 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old.
  • You have been diagnosed with pancreatic ductal adenocarcinoma that cannot be removed by surgery or has spread to other parts of the body.
  • Your cancer has gotten worse after at least one prior standard treatment, or you cannot tolerate standard therapy.
  • A sample of your tumor shows it has the proteins MSLN and/or MUC1 (this will be checked by a special lab test).
  • You are in good enough health to be active and care for yourself (ECOG 0 or 1) and have adequate organ function.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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