How sleep loss and body clock disruption affect insulin resistance
Treatments studied
Part of Hormones & metabolism clinical trials.
This trial studies how losing sleep and disrupting your internal body clock may cause insulin resistance, a condition linked to diabetes. You will stay in a lab for several days to test your body's response to sleep changes and a morning drug called octreotide. The goal is to understand why shift work and jet lag can lead to health problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 45 years old.
- You have a healthy body weight (BMI 18-25) and have not changed weight in the last 6 weeks.
- You are physically and mentally healthy, with no medical conditions or regular medications (including birth control).
- You have a regular sleep schedule (6–10 hours each night) and are neither a morning person nor a night owl.
- You do not smoke, have not donated blood in the last 8 weeks, and have not traveled across time zones or done shift work recently.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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