Clin2
NCT07497958Possibly a fitNot yet recruiting

Warm-up treatment to protect the kidney during tumor removal

Renal Cell Carcinoma (RCC)Renal Function Abnormal

Part of Cancer, Kidney & urinary, Women’s health & pregnancy clinical trials.

This trial tests whether a small 'warm-up' of the blood supply to your kidney before surgery can help prevent kidney damage. This may help keep your kidneys working well after the operation.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
174 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • You must be between 18 and 80 years old.
  • You must be scheduled for surgery to remove part of your kidney (partial nephrectomy) — by any method, including laparoscopic, robotic, or open surgery.
  • Your blood counts and liver function must be within acceptable limits.
  • You must not have severe heart or blood vessel disease, uncontrolled high blood pressure, or uncontrolled diabetes.
  • Your kidney function must not be severely low (eGFR less than 30).
  • You must not have a horseshoe kidney, a single kidney, or be pregnant.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07326280Recruiting
Cold ischemia robot-assisted partial nephrectomy trial

This trial studies a robot-assisted surgery to remove part of the kidney while keeping the kidney cool to protect it. It may help patients who need this type of kidney surgery.

Guangzhou, Guangdong
NCT07386158Recruiting· Phase 2
Immunotherapy before surgery for clear cell kidney cancer

This trial tests whether giving pucotenlimab (an immunotherapy drug) with vorolanib (a targeted therapy) before surgery helps shrink clear cell kidney tumors and makes kidney-sparing surgery safer. It is for people with localized, non-metastatic disease where the tumor is difficult to remove with partial nephrectomy.

Guangzhou, Other (Non U.s.)
NCT07602101Not yet recruiting· Phase 2
Pre-surgery drugs for complex kidney cancer to save kidney

This trial tests whether giving an immunotherapy drug (PD-L1 inhibitor) and an oral medication (anlotinib) before surgery can help shrink complex kidney tumors so that surgeons can remove only part of the kidney, preserving more kidney function. It may help you avoid losing your whole kidney.

NCT07672860Recruiting· Phase 2
UDCA to protect kidneys during partial nephrectomy

This clinical trial is testing whether a medicine called ursodeoxycholic acid (UDCA) can help protect the kidneys during partial nephrectomy (removing only the tumor while keeping the healthy part of the kidney). It is for people with early-stage kidney tumors who will have temporary interruption of blood flow to the kidney during surgery.

Nanjing, Jiangsu
NCT06908902Recruiting
Robot-assisted kidney surgery for early-stage tumors without clamping

This study tests a robot-assisted surgery to remove part of the kidney for T1 tumors without clamping the main artery, which may help preserve kidney function. It may be an option for patients who are healthy enough for major surgery and have a small, early-stage kidney tumor.

Nanjing, Jiangsu
NCT07593040Not yet recruiting· Phase 2
Immunotherapy and targeted drugs before surgery for high-risk kidney cancer

This trial tests a combination of three drugs—an immunotherapy (pembrolizumab) and two targeted therapies (belzutifan and lenvatinib)—given before surgery for high-risk kidney cancer. The goal is to see if this combination can shrink the tumor and improve outcomes after surgery.

Córdoba, Andalusia

Hear when a new Renal Function Abnormal trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.