Study of CM512 for chronic sinusitis with nasal polyps
Treatments studied
Part of Ear, nose & throat clinical trials.
This trial tests a new treatment called CM512 for people with chronic sinusitis and nasal polyps who already took part in an earlier CM512 study. It aims to see if the treatment is safe and effective.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have taken part in the earlier CM512 study for chronic sinusitis with nasal polyps.
- You must not have a tumor (benign or malignant) in your nasal cavity.
- You must wait long enough since previous treatments: at least 10 weeks (or 5 half-lives, whichever is longer) since IL-4 receptor alpha antagonists, and at least 8 weeks (or 5 half-lives) since other biologic drugs or systemic immunosuppressants.
- You must not have had sinus surgery (including polypectomy) within the last 6 months.
- You must not have had a live vaccine within 30 days before the study starts, and you must not plan to get one during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new medication called CM512 for people with chronic sinusitis and nasal polyps. It aims to reduce nasal congestion and improve symptoms.
This study tests an injection called LP-003 that may help reduce nasal polyps and improve breathing. It's for people whose symptoms are not controlled by standard treatments like steroid sprays or surgery.
This study is testing whether certain markers in your blood can predict how well biologic injections (medicines that reduce inflammation) will work for chronic sinusitis with nasal polyps. You'll continue your regular nasal spray and may receive a biologic or a placebo (a shot with no medicine) to see if it improves your symptoms.
This study tests a new drug called BBT002 in healthy people and in patients with chronic sinusitis and nasal polyps, with or without asthma. It aims to see if the drug is safe and effective for reducing symptoms.
This study collects information from people with chronic rhinosinusitis and nasal polyps in both nostrils. By tracking patients over time, researchers hope to learn more about the condition and how to improve care.
This study tests a new medication called CM326 for people with long-term sinus inflammation and nasal polyps. The goal is to see if it reduces symptoms like congestion and improves quality of life. You will receive either the study drug or a placebo.
Hear when a new Chronic Rhinosinusitis With Nasal Polyposis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.