Follow-up Study of CM512 for Chronic Nasal Polyps
Treatments studied
Part of Ear, nose & throat clinical trials.
This is a follow-up study for people who already participated in an earlier CM512 trial for chronic rhinosinusitis with nasal polyps—a condition where growths develop inside the nose and sinuses. The study tests whether CM512 continues to help reduce these polyps.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have completed the earlier CM512 study (Study CM512-102101)
- You have waited at least 10 weeks since stopping IL-4 receptor antagonist medications (or 5 half-lives, whichever is longer)
- You have waited at least 8 weeks since stopping other biologic or immunosuppressant drugs (or 5 half-lives, whichever is longer)
- You have waited at least 6 months since any sinus surgery, including nasal polyp removal
- You do not have a tumor (cancerous or non-cancerous) in your nasal cavity
- You have not received a live vaccine in the past 30 days and will not receive one during the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new medicine called CM326 for people with chronic sinusitis and nasal polyps (growths in the nose). It may help if you still have symptoms despite using steroid sprays or if you cannot take steroids.
This study is looking for markers in the blood that can predict how well certain biologic drugs work for people with chronic sinusitis and nasal polyps. It may help find the right treatment for you if your symptoms are not controlled with standard sprays or after surgery.
This trial tests an injection called LP-003 for people with nasal polyps and chronic sinusitis. It aims to reduce symptoms like nasal congestion and improve quality of life. You may qualify if you have tried other treatments and still have symptoms.
This trial tests a new antibody medicine (CM326) for people with chronic sinusitis and nasal polyps whose symptoms persist despite standard treatments like nasal sprays. It aims to see if the drug can reduce inflammation and improve symptoms.
This trial compares three different biologic medications (injectable drugs) to see which one works best for people with chronic sinusitis and nasal polyps. If you have moderate to severe symptoms and are considering biologic therapy, this study might help find the best option for you.
This trial compares a newer biologic drug (anti-IL-5) plus simple polyp removal to a more extensive sinus surgery. It's for people with chronic sinusitis and nasal polyps who haven't gotten better with standard treatments.
Hear when a new Chronic Rhinosinusitis With Nasal Polyposis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.