Brain radiation with hormone therapy and dalpiciclib for advanced breast cancer
Treatments studied
Part of Brain & nervous system, Cancer, Skin clinical trials.
This trial tests a combination of radiation to the brain, a hormone therapy, and a targeted drug called dalpiciclib for people with advanced breast cancer that has spread to the brain. The goal is to see if this combination can help control the cancer in the brain and elsewhere.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman between 18 and 75 years old.
- You have advanced breast cancer that is hormone-receptor positive and HER2-negative, and it has spread to the brain.
- You have at least one brain tumor that is 1 cm or larger, seen on an MRI.
- You have not had whole-brain radiation before.
- You have not had prior treatment with dalpiciclib for advanced disease.
- You are generally well enough to carry out daily activities (ECOG 0-2).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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