Understanding MS Relapses Without Brain Imaging Changes
Part of Brain & nervous system, Immune system & allergy, Mental health clinical trials.
This study looks at whether people with relapsing-remitting MS can experience symptom flare-ups (relapses) that don't show up on MRI scans. Researchers want to understand if this happens and what it means for your care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old
- You have been diagnosed with relapsing-remitting multiple sclerosis using current diagnostic standards
- You are currently taking disease-modifying therapy (medication to slow MS progression)
- You are experiencing a neurological symptom flare-up lasting between 1 and 7 days (such as weakness, vision changes, or numbness—but not fatigue or pain alone)
- Your most recent MS disability score (EDSS) was between 0 and 7.0, measured within the last year
- You are able to have an MRI scan and are not allergic to the contrast dye used during it
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at “subclinical markers,” meaning early or hidden body changes that may show how relapsing-remitting multiple sclerosis (MS) is doing even when symptoms seem mild. It may help researchers find better ways to monitor MS and detect changes sooner.
This study follows adults with relapsing-remitting multiple sclerosis using MRI scans and blood tests. It aims to understand how the disease behaves and what markers in blood and imaging may relate to changes over time.
This trial uses MRI scans to monitor spinal cord changes in people newly diagnosed with relapsing-remitting MS who have not yet started treatment. It aims to better understand how the disease progresses and could help guide early treatment decisions.
This study uses a special PET-MRI scan to look at brain inflammation in people with relapsing-remitting multiple sclerosis (RRMS). It may help researchers understand how inflammation changes when starting a stronger MS treatment.
This trial uses brain MRI and eye imaging tests to study research markers in people with multiple sclerosis (MS) and related neurologic conditions. It may help researchers better understand these diseases and how they change over time.
This study looks at why some people with relapsing-remitting multiple sclerosis (RRMS) get worse even when they don't have relapses. It uses eye scans and other tests to find early signs of progression, which could help tailor treatments.
Hear when a new Multiple sclerosis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.