Clin2
NCT07559799Likely a fitRecruiting

Melflufen and Dexamethasone for Relapsed Multiple Myeloma

Multiple Myeloma

Part of Blood & lymphatic, Cancer, Heart & circulation, Immune system & allergy clinical trials.

This study tracks how melflufen (a cancer-fighting drug) combined with dexamethasone works in patients with multiple myeloma that has returned or stopped responding to previous treatments. Researchers will monitor your health and quality of life over time to understand the treatment's real-world effectiveness.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
50 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You have multiple myeloma that has relapsed (come back) or become resistant to prior treatments
  • You have previously received at least three specific types of drugs: a proteasome inhibitor, an immunomodulatory agent, and an anti-CD38 monoclonal antibody
  • Your doctor has decided to treat you with melflufen and dexamethasone as your fourth or later line of treatment
  • You are at least 18 years old
  • You are able to provide informed consent and understand the study
  • You are not currently enrolled in an interventional (experimental) clinical trial

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06561854Recruiting· Phase 3
Comparing multiple myeloma treatment with and without dexamethasone

This trial tests whether adding dexamethasone to an antibody-based combination therapy works better for multiple myeloma that has come back after previous treatments. If you have had 1 to 3 prior therapies and are eligible for one of two standard drug regimens, this study may help find the best approach for you.

Paris
NCT07284758Recruiting· Phase 2
Cemsidomide and dexamethasone for relapsed/refractory multiple myeloma

This clinical trial tests a new combination of two medicines (cemsidomide and dexamethasone) for people with multiple myeloma that has come back or stopped responding after at least three prior treatments. The goal is to see if this new drug can help control the cancer when other options have stopped working.

Huntsville, Alabama
NCT07614360Not yet recruiting· Phase 2
Belantamab combination for relapsed multiple myeloma

This trial tests a new way of giving a combination of three drugs—belantamab mafodotin, bortezomib, and dexamethasone—for people with multiple myeloma that has come back or stopped responding to earlier treatments. The goal is to see if a different dosing schedule is more effective and safer.

NCT07227311Recruiting· Phase 2
Belantamab mafodotin combinations for relapsed multiple myeloma

This trial tests a new drug called belantamab mafodotin (a targeted antibody therapy) combined with standard treatments for multiple myeloma that has come back or stopped responding. It looks at three different drug combinations to see which works best for people who have had 1 or 2 prior treatments.

Los Alamitos, California
NCT05922501Recruiting· Phase 2
Test four medicines for relapsed multiple myeloma

This Phase 2 study tests a combination of medicines (isatuximab, belantamab mafodotin, pomalidomide, and dexamethasone) for multiple myeloma that has come back or did not respond to prior treatment. It may help by better controlling the myeloma after standard therapies have failed.

Boston, Massachusetts
NCT01250808AVAILABLE
New drug study for newly diagnosed multiple myeloma

This study is testing new drugs for people recently diagnosed with multiple myeloma, a blood cancer. It aims to see if the new treatment is safe and effective, and it may offer an additional treatment option.

Beijing

Hear when a new Multiple myeloma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.