Obesity's effect on insulin action and fitness in Type 1 Diabetes
Part of Hormones & metabolism, Immune system & allergy clinical trials.
This study examines how excess weight affects how insulin works in small blood vessels and overall fitness in people with Type 1 Diabetes. Researchers want to understand if obesity makes diabetes management harder and whether this knowledge can help future treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 21–50 years old
- If you have Type 1 Diabetes: diagnosed at least 5 years ago, blood sugar control (HbA1c) of 8.5% or lower, using insulin injections or pump
- Body weight in a specific range based on your group (healthy weight, Type 1 Diabetes only, or overweight with Type 1 Diabetes)
- No active serious infections, heart disease, kidney disease, lung disease, or cancer history
- No history of severe low blood sugar episodes you couldn't feel coming, diabetic complications affecting eyes or blood vessels, or ketoacidosis in the past 2 years
- Not a current smoker and haven't quit smoking less than 5 years ago
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies whether changing daily sleep timing (circadian rhythm) and doing physical exercise can improve health outcomes in people who are overweight and have type 1 diabetes (or in some healthy people). It may help by seeing what combinations of routine and activity are most beneficial.
This study looks at how many adults with type 1 diabetes have overweight or obesity. It may help improve future care planning for people living with type 1 diabetes.
This study measures how “blood fats” move in the body after fasting and controlled eating, comparing people with type 1 diabetes to those without diabetes. It may help researchers understand diabetes-related differences in lipid (fat) handling and improve future treatments.
This study looks at how low physical activity, insulin resistance in small blood vessels, and cardiorespiratory fitness connect to diabetes and blood sugar control. You may be eligible if you are generally sedentary and fit within the weight range, and if you do not have certain heart, lung, nerve, or medication factors.
This study looks at how tiny particles called extracellular vesicles affect how your body uses insulin, and whether exercise can make a difference. It is for people with type 2 diabetes (or normal blood sugar) who are not very active and have been on diabetes medication for a long time.
This study tests two different diet approaches to help people with type 1 diabetes who are overweight or obese manage their weight. It aims to find out which eating plan works better for blood sugar control and weight loss.
Hear when a new Type 1 diabetes trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.