Clin2
NCT07577466Likely a fitNot yet recruiting

Cardiac Amyloidosis Screening and Long-Term Follow-Up Study

Amyloidosis CardiacHeart FailureCardiac MRISpectroscopic AnalysisDiagnosisPhenotyping

Part of Brain & nervous system, Genetic & congenital, Heart & circulation, Hormones & metabolism clinical trials.

This study enrolls patients suspected of having or recently diagnosed with cardiac amyloidosis—a condition where abnormal protein deposits thicken the heart muscle. Researchers will use imaging tests like echocardiography and MRI to better understand the disease and track how it changes over time, which may improve future treatment options.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
200 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You are 18 years or older
  • You are being evaluated for amyloidosis or already have a confirmed diagnosis of cardiac amyloidosis before starting treatment
  • Your heart's left ventricular wall (main pumping chamber) is thickened (>12 mm on ultrasound) and shows warning signs of amyloidosis, or your doctor suspects you have amyloidosis based on clinical evaluation
  • You can undergo cardiac MRI imaging without medical contraindications (no certain types of pacemakers, severe obesity, or claustrophobia concerns)
  • You are able to understand and sign the informed consent form and comply with study visits and procedures

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06887283Recruiting
Essen Amyloidosis Registry Study

This study collects information from people with suspected or confirmed amyloidosis. The goal is to learn more about the condition and improve patient care.

Essen, North Rhine-Westphalia
NCT04587648Recruiting
Treating cardiac amyloidosis in heart failure with preserved ejection

This trial studies people with heart failure with preserved ejection fraction (HFpEF) and cardiac amyloidosis (an abnormal protein buildup in the heart). It may help researchers understand better treatment for symptoms and heart function in this group.

Taipei
NCT07784712Not yet recruiting
Right heart biopsy during device placement to detect cardiac amyloidosis

This study tests whether taking a small tissue sample from the right side of the heart during a routine pacemaker or defibrillator procedure can help find a condition called cardiac amyloidosis, which causes stiffening of the heart muscle. It aims to improve early detection in people who already need a cardiac device and may have early signs of the disease.

NCT07154381Recruiting
Hybrid PET/MRI for heart amyloidosis imaging

This study uses a hybrid PET/MRI scanner to take detailed images of the heart in people with amyloidosis. The goal is to see how well this scan shows the buildup of amyloid protein, which could help doctors better diagnose and manage the condition.

Essen, North Rhine-Westphalia
NCT05776212Recruiting
Imaging study for certain heart amyloidosis types and heart thickening

This trial uses special heart imaging to better measure how amyloid deposits affect the heart in people with certain diagnoses. The goal is to understand which imaging signals match your disease and to see if this approach could help guide care.

Groningen
NCT05760287Recruiting
Study of heart ultrasound findings in cardiac amyloidosis

This study looks at how cardiac amyloidosis shows up on heart imaging, especially ultrasound (echocardiography). It may help doctors better describe and track the condition using your exam and test results.

Roma, RM

Hear when a new Heart failure trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.