Immune therapy for sepsis with low white blood cell count
Treatments studied
Part of Blood & lymphatic, Immune system & allergy, Infections clinical trials.
This study tests a new immune-boosting therapy called NAI for people with sepsis who have persistently low lymphocyte counts (a sign of immune weakness). The goal is to see if it can help the immune system recover and improve recovery from sepsis. It is for patients already in the ICU on antibiotics.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older and currently in the ICU with a diagnosis of sepsis (a severe infection causing organ failure).
- Your lymphocyte count (a type of white blood cell) has been low (below 1,000) on two separate blood tests taken at least 12 hours apart, within the first 3 days of sepsis.
- You have already started appropriate antibiotics for the infection.
- You do not have a blood cancer (like leukemia or lymphoma) or a recent stem cell transplant.
- You are not currently taking high-dose steroids or other drugs that suppress the immune system.
- You must be willing to use effective contraception if applicable.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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