Ondansetron to prevent lung injury in patients on ventilators
Treatments studied
Part of Lungs & breathing clinical trials.
This trial tests whether ondansetron, a medicine often used to prevent nausea, can also help prevent further lung damage in patients with a serious lung condition called ARDS who are on a breathing machine. If it works, it could help patients recover from severe breathing problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a serious lung condition called ARDS, confirmed by a doctor.
- You are on a breathing machine (ventilator) and need high levels of oxygen.
- You have been on the ventilator for less than 96 hours.
- You are not expected to be taken off the ventilator within the next 24 hours.
- You do not have certain heart rhythm problems or take medications that could increase the risk of heart rhythm issues.
- You are not pregnant and do not have severe liver disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This study looks at better ways to protect the lungs during mechanical ventilation (breathing support) for people with ARDS, a serious lung injury. It aims to find ways to reduce additional damage to the lungs while on a ventilator.
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