Ondansetron to prevent self-injury in severe lung failure
Treatments studied
Part of Lungs & breathing clinical trials.
This study tests whether ondansetron (a nausea medication) can help prevent patients on breathing machines from accidentally hurting their lungs by fighting against the ventilator. You may qualify if you have severe acute respiratory distress syndrome (ARDS)—a life-threatening lung condition—and are currently on a ventilator.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have moderate-to-severe ARDS (severe lung failure) diagnosed within the past week
- You are on a mechanical ventilator (breathing machine) and have been for less than 4 days
- Your doctors do not expect you to be taken off the ventilator within the next 24 hours
- You do not have a neuromuscular disease that affects your ability to breathe on your own
- You do not have severe liver disease, heart rhythm problems, or a history of abnormal heartbeats
- You are not pregnant and do not have active abdominal or digestive infections
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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