Clin2
NCT07307066Possibly a fitRecruiting

Ventilation feedback study for lung protection in ARDS

ARDS (Acute Respiratory Distress Syndrome)VILI (Ventilator-induced Lung Injury)Respiratory FailureCritical Illness

Part of Lungs & breathing clinical trials.

This study tests a computer system that gives real-time breathing machine advice to help protect the lungs of patients with severe lung injury (ARDS). It may help doctors adjust the ventilator settings to cause less damage.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
208 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You must be between 18 and 75 years old
  • You must be on a breathing machine (ventilator) with a tube in your windpipe, started less than 24 hours ago
  • Your oxygen level in the blood must be very low despite the machine's support (PaO2/FiO2 ratio 200 or less, or SpO2/FiO2 235 or less with SpO2 97% or less)
  • Your chest X-ray or CT scan must show fluid or shadowing in both lungs not explained by other causes like heart failure or fluid overload
  • Your doctors expect you will need the breathing machine for at least 3 more days after joining the study

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07791225Not yet recruiting
Variable breathing settings for lung injury

This trial tests a new way of setting the breathing machine for people with a lung condition called ARDS. It may help improve breathing and recovery compared to standard care.

Birmingham, Alabama
NCT07679802Not yet recruiting
Smart breathing machine method for severe lung injury from pneumonia

This trial tests a new breathing machine method (called time-controlled adaptive ventilation) to see if it helps people with severe lung injury from pneumonia recover better than standard care. If you are already on a ventilator in the ICU, this study may help you breathe more easily while your lungs heal.

Nancy
NCT06790875Recruiting
Comparing two ventilator settings for lung health in ARDS

This study tests two methods of adjusting a ventilator to see which one may better protect the lungs of patients with ARDS. It will help doctors learn how to set the machine to reduce strain on the lungs.

Wuhan, Hubei
NCT06066502Recruiting· Phase 3
Precision ventilation for ARDS

This study tests whether a customized breathing machine approach ("precision ventilation") is better than usual care for patients with ARDS. The goal is to improve oxygen levels and recovery while avoiding lung damage.

Tucson, Arizona
NCT06835881Not yet recruiting
Preventing lung injury from breathing machines in ARDS patients

This study looks at better ways to protect the lungs during mechanical ventilation (breathing support) for people with ARDS, a serious lung injury. It aims to find ways to reduce additional damage to the lungs while on a ventilator.

Paris
NCT07839234Enrolling by invitation
Personalized breathing support for lung injury patients

This trial tests a new way to adjust breathing machine settings for people with a lung condition called ARDS. The adjustments are based on detailed monitoring of the heart and lungs, aiming to improve recovery.

Xiamen, Fujian

Hear when a new Respiratory Failure trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.