Minocycline after stroke clot removal surgery
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether minocycline, an antibiotic, can reduce brain damage when given after successful clot removal surgery for acute stroke. The goal is to see if this medication helps patients recover better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had a stroke caused by a large blood clot in the front of your brain (confirmed on imaging)
- The clot was successfully removed by surgery within the past 24 hours
- You were independent before your stroke (able to walk and care for yourself)
- Your stroke symptoms are moderate in severity (NIHSS score 6–25)
- Your brain scan shows enough viable tissue to treat (ASPECTS ≥6)
- You are willing and able to give informed consent or have a legal representative who can
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests if removing a large blood clot from the brain up to 3 days after a stroke improves recovery compared to standard medical care alone. It is for patients who have a severe stroke and are otherwise healthy enough for the procedure.
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This trial tests whether giving a medication called tirofiban directly into the artery (intra-arterially) after a successful clot removal can improve recovery after a stroke. Tirofiban helps prevent new clots from forming, which may reduce the chance of another stroke.
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