RP-008 Plus Varenicline for Trigeminal Neuralgia Pain
Treatments studied
Part of Brain & nervous system, Mouth & dental clinical trials.
This trial tests a new drug called RP-008 combined with varenicline (a quit-smoking medication) to relieve severe facial pain from trigeminal neuralgia. If you've already tried standard pain medications without enough relief, this combination might help reduce your pain attacks.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18–80 years old
- You have been diagnosed with trigeminal neuralgia (severe facial nerve pain) at least 6 months ago
- Your pain is on only one side of your face, affecting the cheek and/or lower jaw
- You have tried at least one standard anti-epileptic pain medication (like carbamazepine or gabapentin) that didn't work well enough or caused side effects
- You are currently taking a stable dose of trigeminal neuralgia medication and have been for at least 6 weeks
- You can understand and sign an informed consent form
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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