Brain health before and after heart valve replacement
Part of Brain & nervous system, Heart & circulation, Mental health clinical trials.
This study checks how a minimally invasive heart valve procedure affects thinking, memory, and mood. Researchers will test your brain function before and after the valve treatment to see if the procedure impacts how you feel and think.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have severe aortic valve stenosis (a narrowed heart valve) and your doctor recommends a catheter-based valve replacement
- You are at least 18 years old
- You speak and understand German well enough to complete tests and answer questions
- You do not have a life-threatening illness (other than your heart condition) expected to shorten your lifespan to less than one year
- You are willing to give written permission to participate
- You do not have a current diagnosed brain or mental health condition (like dementia, depression, stroke, TIA, migraine, or epilepsy) with symptoms that could affect the study tests
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial is for people with aortic valve disease (aortic valve narrowing, leakage, or a worn-out valve). It tests what the doctors learn from following these patients, and it may help improve future care.
This study tracks patients getting a new heart valve (transcatheter aortic valve implantation) for severe aortic stenosis. It aims to understand long-term outcomes and safety in a real-world registry.
This trial tests whether brain-focused cognitive training before elective heart surgery can help reduce memory and thinking problems afterward. If you qualify, you may do language-based thinking exercises and complete short brain tests around the time of surgery.
This study compares two types of artificial aortic valves to see which one causes fewer tiny blood clots in the brain during implantation. If you need aortic valve replacement, this research may help doctors choose the safest option for you.
This study looks at how a less invasive heart valve procedure affects your day-to-day functioning and overall quality of life. If you’re already being considered for a transcatheter (catheter-based) valve replacement, you may be able to join to help understand what improvements patients experience.
This study tests whether people who have heart bypass surgery or a stent procedure experience any changes in memory, thinking, or brain function afterward. Participants will complete simple computerized tests before and after the procedure.
Hear when a new Aortic Valve Stenosis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.