Amiloride Treatment for Vertebrobasilar Dolichoectasia
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether a blood pressure medication called amiloride can help treat vertebrobasilar dolichoectasia (VBD)—a condition where blood vessels at the base of the brain become abnormally enlarged. The study focuses on patients who have VBD but haven't had a stroke or surgery related to it yet.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18 or older
- Confirmed diagnosis of VBD (a widened blood vessel in the brain) seen on imaging
- No previous stroke from VBD and no prior VBD surgery
- Able to walk and care for yourself with minimal help (mRS score below 4)
- Specific blood marker (SGK1) present in your blood
- Normal liver and kidney function, and normal blood cell and mineral levels
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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