Brain imaging study for Parkinson's and MSA patients
Part of Brain & nervous system, Heart & circulation clinical trials.
This early-stage research trial tests a new brain-imaging tracer called [11C]MODAG-005 to help doctors better understand Parkinson's disease (PD) and multiple system atrophy (MSA). You would undergo PET/CT and MRI scans twice, a few weeks apart, to see how reliable the imaging is.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Diagnosed with Parkinson's disease (PD), multiple system atrophy (MSA), or be a healthy adult without these conditions
- No significant organ problems (liver, kidneys, heart) or unstable medical illnesses
- No metal implants (pacemakers, cochlear implants, etc.) that aren't MRI-safe, and no history of claustrophobia in MRI machines
- Able to have blood drawn multiple times and tolerate an arterial line (small tube in an artery) for blood sampling
- Not pregnant, not breastfeeding, and willing to use effective birth control for 3 months after each scan
- No recent experimental drug use (within 3 months) and no blood donation within 1 week of enrollment
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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