Clin2
NCT07643974Possibly a fitNot yet recruiting

Gentamicin and probiotic wash for neurogenic bladder

Spinal Cord InjuryNeurogenic Bladder (NB)Neurogenic Lower Urinary Tract DysfunctionMultiple SclerosisSpina BifidaUrinary Tract Infection(UTI)

Treatments studied

Part of Brain & nervous system, Genetic & congenital, Immune system & allergy, Infections, Injuries & trauma, Kidney & urinary, Women’s health & pregnancy clinical trials.

This study tests a new bladder wash containing an antibiotic and a probiotic to prevent urinary tract infections in people with neurogenic bladder. It may help reduce infections and improve bladder health.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
48 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older
  • You have a neurologic condition that affects your bladder
  • You have had neurogenic bladder for at least 6 months
  • You do not currently have a urinary tract infection
  • You are not taking antibiotics or have not taken them in the last 2 weeks
  • You do not have other bladder or kidney problems

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07390591Recruiting
Patient views on bladder treatments for urinary symptoms

This study asks patients and caregivers about their experiences with bladder washes (instillations) using lactobacillus or gentamicin to manage urinary symptoms. Your feedback could help improve care for others like you.

Washington D.C., District of Columbia
NCT02331979Recruiting
Neuromodulation trial to improve bladder function after spinal injury

This trial tests a nerve-stimulation approach to improve bladder control in people with spinal cord injury. It specifically targets bladder problems that require clean intermittent catheter use and includes regular testing over 6 months.

Los Angeles, California
NCT04095572Recruiting· Phase 4
Prevention options for recurring bladder infections in women

This trial studies different ways to prevent repeated bladder (urinary tract) infections in women. It may help people who keep getting these infections by testing safer or more effective prevention strategies.

Basel
NCT05230511Recruiting· Phase 2
Bladder wash with LGG probiotic vs saline for nerve bladder

This study tests whether putting a probiotic called LGG into the bladder works better than a saline bladder rinse to help people with a nerve-related bladder problem. It may improve bladder symptoms or reduce bladder infections, compared with standard saline rinses.

Washington D.C., District of Columbia
NCT07308808Recruiting· Early Phase 1
Safety of a live bacteria solution for bladder infections

This trial tests if putting a live bacteria called Lactobacillus crispatus into the bladder is safe for people with spinal cord injury and neurogenic lower urinary tract dysfunction. It may help prevent urinary tract infections without antibiotics.

Washington D.C., District of Columbia
NCT06387329Recruiting· Phase 4
Antibiotic to prevent UTI after bladder Botox

This study tests whether taking a low-dose antibiotic (nitrofurantoin) before a Botox bladder injection can help prevent urinary tract infections. You may be able to join if you are getting Botox for overactive bladder or painful bladder syndrome and do not have frequent UTIs or other health issues that would make the antibiotic unsafe.

Bethesda, Maryland

Hear when a new Neurogenic Lower Urinary Tract Dysfunction trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.