Oral study drug for bipolar depression that hasn't improved with treatment
Part of Mental health clinical trials.
This study tests an investigational oral capsule (KET-AD) taken alongside your usual bipolar depression medication to see if it helps when standard treatments haven't worked well. It aims to improve depressive symptoms in people with treatment-resistant bipolar depression.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old and were first diagnosed with a major depression before age 50.
- You have bipolar disorder (any type) and are currently in a moderate to severe depressive episode.
- You have tried at least two standard treatments for this depression and they did not help enough.
- You have been taking a stable dose of a mood-stabilizing or antidepressant medication for at least 6 weeks.
- You are willing to stop using recreational drugs and limit alcohol during the study.
- You are not pregnant, breastfeeding, or planning to become pregnant, and agree to use contraception if needed.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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