Clin2
NCT07656103Worth exploringNot yet recruiting

Cell therapy for cancer spread to the brain or spinal cord

Brain MetastasisMeningeal MetastasisSpinal Cord Metastasis

Part of Brain & nervous system, Cancer clinical trials.

This trial tests an experimental cell therapy (QH101) for people whose solid tumors have spread to the brain or spinal cord and haven't responded to standard treatments. The cells are injected directly into the fluid around the brain and spinal cord to try to fight the tumors there.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
7 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 or older
  • You have a solid tumor cancer (like lung, breast, or melanoma) that has spread to your brain, the lining of your brain, or your spinal cord
  • You have already tried standard treatments (like whole-brain radiation or surgery) and they didn't work, or there is no standard treatment available
  • You are generally able to take care of yourself (ECOG score 2 or less, or KPS 60 or above)
  • Your blood counts are within a certain range, and your liver, kidney, and clotting functions are normal
  • You do not have tumors in your brainstem or the very top part of your spinal cord

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07552233Recruiting
NK Cell Therapy for Recurrent Brain Tumors

This trial tests a new type of immune cell therapy (NK cells) for patients with malignant brain tumors that have come back or worsened despite previous treatment. The goal is to see if these specially prepared immune cells can help fight the cancer.

Beijing, Beijing Municipality
NCT07264569Recruiting· Phase 1/Phase 2
Testing a new drug for lung cancer that has spread to the brain or spinal fluid

This trial tests a new drug called BioTTT001 for people with non-small cell lung cancer (NSCLC) that has spread to the fluid around the brain or the lining of the brain (leptomeninges). The goal is to see if the drug is safe and can help control the cancer.

Zhengzhou, Henan
NCT06742593Not yet recruiting· Phase 1
Study of a new drug for cancers that spread to the brain or spinal cord

This study tests a new drug called MT027 for people whose solid tumors (like lung, breast, or colon cancer) have spread to the brain, the lining of the brain, or the spinal cord. It aims to see if the drug is safe and can help shrink or control these cancers.

Beijing, Beijing Municipality
NCT07318818Recruiting· Phase 1/Phase 2
Revised cell therapy for recurrent brain cancer

This trial tests a new cell therapy (P134 cells) for people whose glioblastoma has come back after standard treatments like radiation or chemotherapy. The therapy uses a patient's own immune cells (PBMCs) to target cancer cells that have specific markers (CD44 or CD133). It also requires a small procedure to place a reservoir under the scalp for drug delivery.

Beijing
NCT06342336Recruiting· Phase 1
HS-IT101 injection for advanced solid tumors

This trial tests an experimental cell therapy (HS-IT101) for people with advanced solid tumors that have not responded to standard treatments. It uses immune cells from your own tumor to fight cancer, and researchers want to see if it is safe and effective.

Beijing, Beijing Municipality
NCT07601204Not yet recruiting· Phase 1/Phase 2
Treatment for advanced head and neck cancer

This trial tests a new treatment for patients whose head and neck cancer has returned or spread and cannot be cured with local therapy. It aims to see if the drug can shrink tumors or slow the disease, potentially offering a new option when standard treatments have stopped working.

Beijing, Beijing Municipality

Hear when a new Brain Metastasis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.