Testing dexmedetomidine for blood flow in septic shock
Treatments studied
Part of Blood & lymphatic, Genetic & congenital, Heart & circulation, Infections clinical trials.
This study tests whether adding a sedative called dexmedetomidine, along with your current care, can improve blood flow in small blood vessels under the tongue for people with septic shock in the ICU.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 85 years old.
- You have septic shock and are on a medication (norepinephrine) to keep your blood pressure up.
- You are on a breathing machine (ventilator) in the intensive care unit.
- You already need sedation, but are not using the study drug yet.
- You have a special monitoring catheter (PiCCO) in place to check your circulation.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a medicine called anisodamine can improve blood flow in tiny vessels (microcirculation) under your tongue and help stabilize blood pressure in patients with septic shock. It may offer a new way to support recovery in the ICU.
This study tests a medication called esmolol to see if it helps blood flow in tiny blood vessels under the tongue for people with septic shock. If you have a fast heart rate despite treatment, this trial may help your doctors better manage your condition.
This trial tests if the drug dexmedetomidine can help calm the stress response in people with severe infection-related shock. It compares this approach with standard care to see if it improves outcomes for patients in the intensive care unit.
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This trial studies how blood flow and organ “perfusion” look in ICU patients who are struggling with infection and low blood pressure. It may help doctors better measure and manage shock by comparing hemodynamic readings during standard treatment.
This trial tests if giving methylene blue early can improve blood flow in patients with sepsis who still have low blood pressure despite fluids and are on high doses of noradrenaline. It aims to help stabilize their condition.
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