Landiolol for heart-rate and circulation problems in septic shock
Treatments studied
Part of Infections clinical trials.
This Phase 3 trial tests whether landiolol (a short-acting heart-rate–lowering medicine) can improve blood circulation in adults with septic shock whose heart rate is too fast. Doctors will also check that the medication is safe in this critical-care setting.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be an adult age 18 or older
- Have septic shock that is treated with noradrenaline (a blood-pressure support medicine) and have a fast heart rate over 100
- Be in critical care for at least 6 hours but less than 24 hours before starting the study, with stable noradrenaline doses for the prior 2 hours
- Have a heart rhythm called sinus tachycardia that the care team feels should be treated (not a compensating response)
- Be able to give consent (or a legal/emergency consent process can be used) and have social security coverage
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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