Pramipexole for depression in bipolar disorder
Treatments studied
Part of Brain & nervous system, Mental health clinical trials.
This trial tests whether pramipexole, a medication that may boost dopamine activity, helps improve symptoms of depression and loss of interest (anhedonia) in people with bipolar disorder. Participants will receive either pramipexole or a placebo (inactive pill) to see if it helps.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 80 years old.
- You must have a diagnosis of bipolar disorder (type I or II).
- You must currently be in a depressive episode that has lasted at least 2 weeks (up to 18 months).
- You must be taking at least one mood-stabilizing medication, such as lithium, valproate, or an antipsychotic.
- You must have significant loss of interest or pleasure (anhedonia) in daily activities.
- You must not be pregnant, breastfeeding, or planning pregnancy during the trial.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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