Brain radiation with REYOBIQ for leptomeningeal metastases
Part of Brain & nervous system, Cancer clinical trials.
This trial tests whether adding a drug called REYOBIQ to whole brain radiation or a targeted radiation technique (PCSI) can help people whose cancer has spread to the lining of the brain or spinal cord. The goal is to find out if this combination is safe and effective.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be at least 18 years old.
- You must have a confirmed diagnosis of cancer that has spread to the lining of the brain or spinal cord (leptomeningeal metastases).
- You need to be able to care for yourself most of the time (Karnofsky performance status score of 60 to 100).
- Your liver, kidney, and blood cell counts must be within acceptable ranges as determined by standard tests.
- You cannot have certain other serious medical conditions, like uncontrolled infections, heart problems, or a history of certain strokes or seizures within the last few months.
- You cannot have had radiation therapy to the whole brain before, and you must not have a shunt (a tube to drain fluid) in your brain.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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