Better breathing with careful sedation in low oxygen
Part of Lungs & breathing clinical trials.
This trial tests if adjusting sedation levels to match breathing effort can help patients with low oxygen levels. It aims to reduce discomfort and breathing problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- Your oxygen level in the blood must be low (PaO2/FiO2 ratio 200 or less).
- Your carbon dioxide level must be below 45 mmHg.
- You should have symptoms like shortness of breath or discomfort (score 4 or more on a 0-10 scale), or rapid breathing (25 or more breaths per minute), or low carbon dioxide, or pain (score 4 or more).
- You cannot have severe asthma or COPD flare-up, or need oxygen at home.
- You cannot have sudden heart failure, unstable blood pressure, severe acidosis, or low consciousness.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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